JAB HAPPY
I lost 10.5st in 8 months on fat jabs but suffered 3 side effects – I wasn’t prepared for how fast it happened
Find out everything you need to know about fat jabs below
CHARLIE Sadler had never felt so low in his life - weighing 34 stone and stuck in a painful cycle of comfort eating, he saw no way out.
The 31-year-old had battled with his weight throughout adulthood, and with every passing year, his self-confidence dipped lower.
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“My self-esteem had always been bad - but I was trapped in a bad relationship and used food to try to fill the emotional gap,” he says.
“It just made things worse.”
Charlie tried various methods to lose weight, from online weight loss programmes to the gym.
But no approach was sustainable.
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“I’d burn myself out at the gym, only to be starving all the time,” he explains.
“I wasn’t training my brain to eat in a way that would support my body. It was so difficult and disheartening.”
Working from his Tamworth home as an account executive, Charlie found himself constantly picking from the fridge out of habit, boredom and isolation.
He felt trapped by his size and struggled to navigate daily life.
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He thought a trip to Barcelona for a stag do five years ago would cheer him up, but the journey made him feel worse.
When he tried to do up his seatbelt it wouldn’t fit and he had to ask the steward for help with an extension belt.
I've lost 3 stone in 8 months on fat jabs - there's a common error new starters are making & it means nasty side effects
“That filled me with shame," he said. "It made me dread flying. I felt so self-conscious and embarrassed.
"It was a reminder that I wasn’t in control of my own body.
“Being a big man is hard. Not fitting into public transport seats, being constantly judged for being fat - it used to break my heart.
"I felt so uncomfortable all the time. I just wanted to stay at home 24/7 because I was safe there.”
The breaking point came when Charlie, 5ft10 in height and weighing 34 stone at his heaviest, asked his doctor for help and was met with indifference.
“I was just advised I was too big and needed to change," he said.
"Which, fair enough, I did. But I didn’t feel like I was being given a real solution.
"I felt like I was talking to a brick wall.”
Being a fat man is hard...I just wanted to stay at home 24/7 because I was safe there
Charlie Sadler
He confided in a friend who recommended Juniper, a service that offered access to weight loss medication Wegovy to help with appetite regulation.
Wegovy (semaglutide) is an approved weight management medication available on the NHS for individuals with obesity, who are overweight, or have weight-related health conditions.
It can be prescribed by specialist weight management services after a referral from a GP.
Charlie was nervous, but knew he needed to give it a try and started taking the drug in July last year.
“The idea of taking a medication like that felt odd at first,” Charlie said.
“I had a lot of doubts. But then I realised that this was my chance. I wasn’t just sitting back waiting for a miracle. I was taking control.”
What are the other side effects of weight loss jabs?
Like any medication, weight loss jabs can have side effects.
Common side effects of injections such as Ozempic include:
Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts.
Vomiting: Can occur, often in conjunction with nausea.
Diarrhea: Some people experience gastrointestinal upset.
Constipation: Some individuals may also experience constipation.
Stomach pain or discomfort: Some people may experience abdominal pain or discomfort.
Reduced appetite: This is often a desired effect for people using Ozempic for weight loss.
Indigestion: Can cause a feeling of bloating or discomfort after eating.
Serious side effects can also include:
Pancreatitis: In rare cases, Ozempic may increase the risk of inflammation of the pancreas, known as pancreatitis, which can cause severe stomach pain, nausea, and vomiting.
Kidney problems: There have been reports of kidney issues, including kidney failure, though this is uncommon.
Thyroid tumors: There’s a potential increased risk of thyroid cancer, although this risk is based on animal studies. It is not confirmed in humans, but people with a history of thyroid cancer should avoid Ozempic.
Vision problems: Rapid changes in blood sugar levels may affect vision, and some people have reported blurry vision when taking Ozempic.
Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin.
Charlie started to feel the difference as soon as he injected his first dose, although he also experienced three side effects - dry mouth, headaches, and low moods.
“My appetite went right down and I lost the first few stone very quickly," he said.
"It was a combination of desperation and the side effects kicking in.
“I wasn’t prepared for how fast it happened, but the results spoke for themselves. It was like my body just clicked into gear.”
Over time the weight loss slowed down to a healthier pace, and Charlie started to feel positive effects on his mind as well as his body.
“I began to feel more in control, more focused, and more motivated to keep going," Charlie said.
"It wasn’t just about looking different. It was about feeling different.
"I feel like a new man. I never imagined I’d be able to say that. It’s like I’ve been given a second chance."
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He has now lost 10.5st, stopped comfort eating and is hopeful for the first time in years.
While he has shrunk in size and bought a completely new wardrobe, the most transformational aspect has been the improvement in his confidence.
He no longer feels trapped by his weight and is able to travel without worrying about fitting into seats or being judged in public.
Most importantly, he feels good about himself.
“I think there’s an unhealthy attitude toward men and weight loss,” Charlie adds.
“We make jokes about being unhealthy, but we never get serious about it. Men are told to be brave and man up, but we need to change that.
“I used to think there was something wrong with me for needing help. But once I realised it wasn’t a weakness, I started talking about it more.
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"I’ve had friends who have opened up to me since I started this journey.
“It’s OK for men to seek help. It’s OK to take control of your health. That’s why I’m sharing my story.”
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Everything you need to know about fat jabs
Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases.
Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK.
Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market.
Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year.
How do they work?
The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight.
They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists.
They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high.
Can I get them?
NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics.
Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure.
GPs generally do not prescribe the drugs for weight loss.
Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk.
Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health.
Are there any risks?
Yes – side effects are common but most are relatively mild.
Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea.
Dr Sarah Jarvis, GP and clinical consultant at patient.info, said: “One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.”
Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia.
Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health.
Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines.
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